This article re-examines the circumstances, reasons and date of taking Tigranes II the Great into hostage by the Parthians from a new perspective.In the light of in-formation from late Babylonian cuneiform, Greco-Roman, ancient Armenian and ancient Georgian sources, the prevailing scholarly Accessories opinion that the surrender of Prince Tigranes as a hostage was due to the demands of the Parthian side following the Armenian military defeat by Parthian King Mithridates II is challenged and refuted.A new interpretation of events logically connects the accounts of Justin [25:322] and Strabo [42:336-340] regarding taking Tigranes II the Great hostage, which is confirmed by the late Babylonian cuneiform tablet, with information from Strabo Headband [43:224-225] of successful Armenian resistance against repeated Parthian aggression.